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| Date | Location | Result | |
| May 15, 2021 | Decatur, Ill. | Millikin 8, Illinois Wesleyan 0 | Box score |
| May 14, 2021 | Decatur, Ill. | Illinois Wesleyan 7, North Central 3 | Box score |
| May 14, 2021 | Decatur, Ill. | Millikin 1, Illinois Wesleyan 0 | Box score |
| May 08, 2021 | Bloomington, Ill. | Ill. Wesleyan 4, Carthage 1 | Box score |
| May 06, 2021 | Bloomington, Ill. | Ill. Wesleyan 4, Wheaton (IL) 1 | Box score |
| May 03, 2021 | Greencastle, Ind. | DePauw 4, Illinois Wesleyan 2 | Box score |
| May 03, 2021 | Greencastle, Ind. | DePauw 5, Illinois Wesleyan 2 | Box score |
| May 01, 2021 | Naperville, Ill. | Ill. Wesleyan 7, North Central 5 | Box score |
| May 01, 2021 | Naperville, Ill. | Ill. Wesleyan 3, North Central 1 | Box score |
| Apr 30, 2021 | Bloomington, Ill. | Ill. Wesleyan 4, Millikin 1 | Box score |
| Apr 30, 2021 | Bloomington, Ill. | Millikin 7, Ill. Wesleyan 2 | Box score |
| Apr 27, 2021 | Bloomington, Ill. | North Central 4, Ill. Wesleyan 0 | Box score |
| Apr 27, 2021 | Bloomington, Ill. | North Central 9, Ill. Wesleyan 2 | Box score |
| Apr 25, 2021 | Chicago, Ill. | Ill. Wesleyan 8, North Park 5 | Box score |
| Apr 25, 2021 | Chicago, Ill. | Ill. Wesleyan 7, North Park 2 | Box score |
| Apr 21, 2021 | Bloomington, Ill. | Ill. Wesleyan 6, Augustana 1 | Box score |
| Apr 21, 2021 | Bloomington, Ill. | Ill. Wesleyan 5, Augustana 4 | Box score |
| Apr 18, 2021 | Waukesha, Wis. | Ill. Wesleyan 5, Carroll 4 | Box score |
| Apr 18, 2021 | Waukesha, Wis. | Carroll 4, Ill. Wesleyan 1 | Box score |
| Apr 17, 2021 | Kenosha, Wis. | Ill. Wesleyan 3, Carthage College 2 | Box score |
| Apr 17, 2021 | Kenosha, Wis. | Ill. Wesleyan 4, Carthage College 0 | Box score |
| Apr 15, 2021 | Bloomington, Ill. | Ill. Wesleyan 3, Carthage 1 | Box score |
| Apr 15, 2021 | Bloomington, Ill. | Ill. Wesleyan 2, Carthage 0 | Box score |
| Apr 9, 2021 | Wheaton, Ill. | Ill. Wesleyan 3, Wheaton (IL) 0 | Box score |
| Apr 9, 2021 | Wheaton, Ill. | Ill. Wesleyan 13, Wheaton (IL) 3 | Box score |
| Apr 06, 2021 | Rock Island, Ill. | Illinois Wesleyan 7, Augustana 2 | Box score |
| Apr 06, 2021 | Rock Island, Ill. | Augustana 1, Illinois Wesleyan 0 | Box score |
| Apr 03, 2021 | Bloomington, Ill. | Ill. Wesleyan 13, North Park 3 | Box score |
| Apr 03, 2021 | Bloomington, Ill. | Ill. Wesleyan 9, North Park 8 | Box score |
| Apr 02, 2021 | Bloomington, Ill. | Ill. Wesleyan 4, WashU 3 | Box score |
| Apr 02, 2021 | Bloomington, Ill. | WashU 7, Ill. Wesleyan 5 | Box score |
| Mar 31, 2021 | Decatur, Ill. | Ill. Wesleyan 2, Millikin 1 | Box score |
| Mar 31, 2021 | Decatur, Ill. | Millikin 7, Ill. Wesleyan 6 | Box score |
| Mar 28, 2021 | Bloomington, Ill. | Ill. Wesleyan 16, Carroll 1 | Box score |
| Mar 28, 2021 | Bloomington, Ill. | Ill. Wesleyan 6, Carroll 0 | Box score |
| Mar 24, 2021 | Bloomington, Ill. | Ill. Wesleyan 6, Wheaton 3 | Box score |
| Mar 24, 2021 | Bloomington, Ill. | Wheaton 9, Ill. Wesleyan 0 | Box score |
| Mar 21, 2021 | Bloomington, Ill. | Elmhurst 5, Ill. Wesleyan 4 | Box score |
| Mar 21, 2021 | Bloomington, Ill. | Elmhurst 8, Ill. Wesleyan 4 | Box score |
| Mar 20, 2021 | Lexington, Ky. | Transylvania 1, Ill. Wesleyan 0 | Box score |
| Mar 20, 2021 | Lexington, Ky. | Trine 1, Ill. Wesleyan 0 | Box score |
| Feb 18, 2021 | Peoria, Ill. | Ill. Wesleyan 10, Illinois College 0 | Box score |
| Feb 18, 2021 | Peoria, Ill. | Ill. Wesleyan 6, Illinois College 4 | Box score |